fbpx
Sign up now!
Don't show this again
Sweepstakes Rules

We’re glad you’re enjoying Poultry Health Today.
Access is free but you’ll need to register to view more content.
Already registered? Sign In
Tap to download the app
X
Share
X
REPORTSCollect articles and features into your own report to read later, print or share with others

Create a New Report

Favorites

Read Later

Create a new report

Report title (required) Brief description (optional)
CREATE
X
NEXT
POULTRY PORK FISH
follow us


You must be logged in to edit your profile.

Favorites Read Later My Reports PHT Special Reports
Poultry Health Today is equipped with some amazing (and free) tools for organizing and sharing content, as well as creating your own magazines and special reports. To access them, please register today.
Sponsored by Zoetis

Sponsored By Zoetis

.
Playicon

Is genetics the key for lasting IBV immunity?

Manipulating the immune response may be one way infectious bronchitis virus (IBV) is controlled in the future, predict researchers studying genetic lines of poultry.

Rodrigo Gallardo, DVM, PhD, associate professor of poultry medicine at the University of California—Davis, told Poultry Health Today that a study was initiated more than 3 years ago to search for new preventive IBV strategies.

The objective isn’t to develop a new genetic line of birds, however. The researchers are looking for molecules or cells that provide IBV resistance when stimulated, he said.

The research started by challenging more than 10 different genetic lines of leghorn chickens with IBV. That process, which itself took more than 2 years, resulted in identifying one line that is relatively resistant to IBV and one that is susceptible to the virus. With the focus narrowed to two genetic lines, the researchers are now studying chickens’ innate and adaptive immune responses, Gallardo said.

Innate immunity — a host’s first line of defense against infection — is “nonspecific” and difficult to measure. Adaptive immunity is easier to measure since it produces a local antibody response to a challenge, he explained.

The resistant line has shown a strong adaptive immune response by producing a large quantity of IgA and IgG antibodies. Chickens in the IBV-resistant line don’t have many respiratory signs during an IBV challenge and have less inflammation in the trachea than birds in the susceptible line, he noted.

 




Posted on December 3, 2018

tags: , , ,
RELATED NEWS
  • ‘Reverse genetics’ may offer new IBV vaccine targets

    Researchers at The Pirbright Institute in the UK report that a recent study provides evidence that mutations in the genetic code for non-structural proteins “offer a promising way” to make vaccines against infectious bronchitis virus (IBV) safer.

  • Why ‘vaccinated’ chickens still get infected with IBV — and what to do about it

    While many vaccines and vaccination programs effectively protect against the highly contagious infectious bronchitis virus in poultry, outbreaks of the disease still occur in vaccinated flocks.

  • Poultry industry can learn from COVID-19

    Biosecurity is not sufficient to control avian coronaviruses like infectious bronchitis in commercial poultry, no matter how good it is, said Mark Jackwood, PhD, a molecular virologist and professor of avian medicine at the University of Georgia.

  • Poor IBV vaccine performance in broiler study underlines need for surveillance

    A whole-complex study of broiler breeders in Georgia found underwhelming infectious bronchitis vaccine performance – but with better surveillance and protocols, outcomes could be improved.




You must be logged in to edit your profile.

Google Translate is provided on this website as a reference tool. However, Poultry Health Today and its sponsor and affiliates do not guarantee in any way the accuracy of the translated content and are not responsible for any event resulting from the use of the translation provided by Google. By choosing a language other than English from the Google Translate menu, the user agrees to withhold all liability and/or damage that may occur to the user by depending on or using the translation by Google.