fbpx
Sign up now!
Don't show this again

Thank you for confirming your subscription!

(And remember, if ever you want to change your email preferences or unsubscribe, just click on the links at the bottom of any email.)

We’re glad you’re enjoying Poultry Health Today.
Access is free but you’ll need to register to view more content.
Already registered? Sign In
Tap to download the app
X
Share
X

REPORTS

Collect articles and features into your own report to read later, print or share with others

Create a New Report

Favorites

Read Later

Create a new report

Report title (required) Brief description (optional)
CREATE
X
NEXT
POULTRY PORK
follow us


You must be logged in to edit your profile.

Favorites Read Later My Reports PHT Special Reports
Poultry Health Today is equipped with some amazing (and free) tools for organizing and sharing content, as well as creating your own magazines and special reports. To access them, please register today.
Sponsored by Zoetis

Sponsored By Zoetis

.

Broiler chicks show less tendon swelling, weight suppression in reovirus vaccine study

A recent study showed that broiler chicks receiving higher reovirus antibody levels from conventionally vaccinated hens had a lower incidence of tendon swelling and were protected from weight suppression caused by Variant Group-1 (VG-1), Kalen Cookson, DVM, director of clinical research, Zoetis Inc., said at the 2014 International Poultry Scientific Forum.1

Zoetis veterinarians initiated a study after a substantial increase in reovirustenosynovitis occurred in several US broiler-producing regions during the winter of 2011-2012.

Previous research has indicated that live reovirus vaccines such as S-1133 given to broilers may have limited efficacy against VG-1, but a study of maternal antibody levels from commercial killed vaccines had not been reported, Cookson explained.

In the study, investigators raised 400 Cobb-500 chicks from two breeder flocks, designated as Flocks A and B, on fresh shavings until 5 days of age, when they were commingled and placed into floor pens.

The researchers then initiated three challenge treatment groups: One received classic S-1133 reovirus via footpad injection, the second group received VG-1 reovirus via footpad injection and the third group received VG-1 via intratracheal inoculation. A fourth group received saline only in the footpad and served as a control.

Investigators measured bodyweight and footpads every 3 days until 21 days of age. They also tested serum for reovirus antibodies and confirmed that chicks had antibodies only to classic reovirus vaccines, not to VG-1. Flock A had reovirus antibodies that were about 50% higher than Flock B’s.

Zoetis veterinarians initiated a study after a substantial increase in reovirus tenosynovitis occurred in several US broiler-producing regions during the winter of 2011-2012.

Weight gain only major difference

The only substantial finding between flocks was that Flock A had higher weight gain after VG-1 challenge, and the difference was statistically significant (p ≤ 0.05), Cookson said.

The incidence of tendon swelling was lowest in the group that received S-1133, followed by VG-1 administered in the footpad. It was highest — 80% — in broilers that received intratracheal VG-1, Cookson continued.

Broilers challenged in the footpad had an incidence of hydropericardium — a noninflammatory accumulation of watery fluid in the pericardial cavity — that was low at 8%-12%, compared to 40%-46% in the group challenged with VG-1 via the intratracheal route, he said.

Hardy virus

There have been numerous field reports of VG-1 vertical shedding — from hens to chicks — but the high incidence of hydropericardium and tendon swelling in the intratracheal challenge group demonstrates that VG-1 is also quite infectious via horizontal, or chicken-to-chicken, exposure, Cookson noted. Therefore, once this virus is introduced, it is capable of sustaining itself on farms over consecutive flock placements.

“A properly chosen autogenous vaccine may be the most effective way to help protect against VG-1 challenge, but this study suggests that higher ‘classic’ antibodies can also help provide a moderating benefit,” Cookson concluded.

 

 

1 Cookson K, et al. Comparison of reovirus challenge viruses s-1133 and variant Group-1 in two commercial broiler flocks with different maternal immunity levels. Abstracts, International Poultry Scientific Forum, Atlanta, 2014.

 

 

 




Posted on April 2, 2015

tags: ,
RELATED NEWS



You must be logged in to edit your profile.

Google Translate is provided on this website as a reference tool. However, Poultry Health Today and its sponsor and affiliates do not guarantee in any way the accuracy of the translated content and are not responsible for any event resulting from the use of the translation provided by Google. By choosing a language other than English from the Google Translate menu, the user agrees to withhold all liability and/or damage that may occur to the user by depending on or using the translation by Google.