fbpx
Sign up now!
Don't show this again
Sweepstakes Rules

We’re glad you’re enjoying Poultry Health Today.
Access is free but you’ll need to register to view more content.
Already registered? Sign In
Tap to download the app
X
Share
X
REPORTSCollect articles and features into your own report to read later, print or share with others

Create a New Report

Favorites

Read Later

Create a new report

Report title (required) Brief description (optional)
CREATE
X
NEXT
POULTRY
follow us


You must be logged in to edit your profile.

Sponsored by Zoetis

Sponsored By Zoetis

.
Xdv6ttqir50wziiiz1e7

Better protection shown with recommended Marek’s disease vaccine dose in two genetic lines

The recommended dose of two Marek’s disease virus (MDV) vaccines provided better protection in two genetic lines of meat-type chickens compared to a lower dose, the results of a recent study show, Tarsicio Villalobos, director of technical services, Zoetis, said at the AAAP conference.1

In their controlled study, investigators sought to determine if the origin and dose of CVI988-strain MDV vaccines affect the efficacy against an early challenge with very virulent (vv) MDV.

Commercial hatchery eggs from two different genetic lines were injected in ovo at 18 days of incubation. They received Vaccine A, a competitor product, or Zoetis’ Poulvac® Ovoline CVI. Each vaccine was administered at the higher recommended dose of 4,000 plaque-forming units or at a lower dose. At hatch, females were sorted out, injected with ceftiofur and transported to North Carolina State University, where they were challenged with the vvMDV strain 648A.

At 7 days of age, there were no significant differences in bodyweight between birds that received the high or low dose of either vaccine, but by 21 days of age, bodyweight was significantly better in birds that had received the full, recommended dose of Poulvac Ovoline CVI compared to a group of controls that were not vaccinated and challenged, Villalobos said.

In addition, protection against the challenge as determined by the presence of MD lesions was significantly better at 51 days of age in birds that had received the recommended dose of both vaccines compared to the low dose and control. Both vaccines at the full dose did not seem to be affected by the genetic lines used in the study, he said.

1 Villalobos T, et al. american Veterinary Medical Association Convention notes; American Association of Avian Pathologists Symposium, 2013, Chicago. Zoetis inc. study #05-11-70aQO.

 




Posted on January 15, 2014

tags: , ,
RELATED NEWS
  • Replication, coverage vary among MD vaccination programs for long-lived birds

    DISCOVERIES: Marek’s disease (MD) vaccination programs for breeders and layers can vary significantly in the replication and coverage they provide, a finding that should be considered when planning an MD-control strategy for long-lived birds

  • Tooling up for better disease protection through applied research

    Vaccines are powerful, widely used tools for managing poultry diseases. How can the industry keep pace with variant viruses and other challenges?

  • Recombinant vaccines for poultry: How to maximize results

    Proper vaccine handling, dosage and administration are key to ensuring thorough and effective coverage. That statement is particularly true when talking about recombinant-vector vaccines.

  • ‘Reverse genetics’ may offer new IBV vaccine targets

    Researchers at The Pirbright Institute in the UK report that a recent study provides evidence that mutations in the genetic code for non-structural proteins “offer a promising way” to make vaccines against infectious bronchitis virus (IBV) safer.




You must be logged in to edit your profile.

Google Translate is provided on this website as a reference tool. However, Poultry Health Today and its sponsor and affiliates do not guarantee in any way the accuracy of the translated content and are not responsible for any event resulting from the use of the translation provided by Google. By choosing a language other than English from the Google Translate menu, the user agrees to withhold all liability and/or damage that may occur to the user by depending on or using the translation by Google.